The residents of a rural mining town discover that an unfortunate chemical spill has caused hundreds of little spiders to mutate overnight to the size of SUVs. It's then up to mining engineer Chris McCormack and Sheriff Sam Parker to mobilize an eclectic group of townspeople, including the Sheriff's young son, Mike, her daughter, Ashley, and paranoid radio announcer Harlan, into battle against the bloodthirsty eight-legged beasts.

It is 1776 in colonial South Carolina. Benjamin Martin, a French-Indian war hero who is haunted by his past, now wants nothing more then to live peacefully on his small plantation, and wants no part of a war with the most powerful nation in the world, Great Britain. Meanwhile, his two eldest sons, Gabriel and Thomas, can't wait to enlist in the newly formed "Continental Army." When South Carolina decides to join the rebellion against England, Gabriel immediately signs up to fight...without his...